THE GTEx PROJECT
Furthering the study of human gene expression and genetic variation.
The National Institutes of Health’s Genotype-Tissue Expression (GTEx) project was developed to help researchers better understand the relationship between genetic variation and gene expression in normal human postmortem tissue. The end goal was to determine how such differences influence susceptibility to disease.
GTEx has created a comprehensive public resource for the research community to evaluate tissue-specific gene expression and regulation in many different tissues and disease types. GTEx data is accessible through the National Center for Biotechnology Information’s database of Genotypes and Phenotypes (dbGaP) and at the GTEx Portal. Tissue image files are available for download. Thousands of biospecimens are available for research, including tissue biospecimens as well as RNA, DNA, blood, and cell lines. The Standard Operating Procedures guiding the collection are also available. The GTEx biospecimens are available from the Broad Institute, Cambridge, MA.
SELECT GTEx CONSORTIUM PUBLICATIONS
THE GTEx CONSORTIUM
The GTEx Consortium Analysis Working Group (AWG) performed the statistical analysis and interpretation of the data. The GTEx AWG was open to all academic, government and private sector scientists interested in participating in a collaborative open process to facilitate the comprehensive analysis of genotype, gene expression, and other molecular phenotypes across multiple human tissues.
