Vocabularies for Biobanking
Medical research requires large-scale data integration on institutional, inter-institutional, and international levels. The data annotation accompanying human specimens is an important part of that data integration challenge. Research institutions often operate multiple biobanks to fulfill diverse research needs and they may use different data representation and schemata. A biobanking ontology is a formal naming and definition of biobanking terms, procedures and protocols that can enable the effective integration of biobank-related data. Utilizing and/or harmonizing on pre-existing ontological representations may allow for linking of data from biobanks to other biological and biomedical data repositories. Ontologies are also very important for translational research because of the capability to link data across other disciplines from basic science to clinical research.
The Open Biological and Biomedical Ontology (OBO) Foundry 
is a collective of ontologies with a mission to
develop ontologies that are logically well-formed and scientifically accurate. Within the OBO is the Ontology for Biobanking (OBIB), which was created for the
annotation and modeling of biobank repository and biobank management. BBRB, in collaboration with the NCI Center for Biomedical Informatics and Information
Technology (CBIIT) and the OBIB consortium, has worked to create standard terminology and definitions (vocabularies) for biospecimen
collection throughout a project life cycle. These vocabularies were used throughout the biospecimen collection and clinical data management that supported the
Biospecimen Preanalytical Variables (BPV) and Genotype-Tissue Expression (GTEx)
projects. They are now available to the public on the following databases:
NCI Cancer Data Standards Registry and Repository (caDSR)