Biobanking for Precision Medicine Seminar Series

Dr. Nilsa Ramirez, Dr. Scott Jewell and Dr. Shannon McCall: Case Studies on Biobanking Infrastructures that Enable Return of Results

March 29, 2022

View the Webinar: Part 1 and Part 2

Abstracts:

Case Study by Dr. Ramirez: Biobanking in the Context of Clinical Trials - The Biopathology Center Experience
The Biopathology Center provides biobanking services to several NCI- sponsored clinical trial efforts (e.g., COG, SWOG, NRG Oncology, EET). For some of the clinical trials sponsored by these groups, it is necessary or required to support biospecimen processing in a CAP accredited/CLIA certified environment. Specimens processed under these regulatory requirements can be used for downstream clinical testing, patient stratification, and targeted treatments. This presentation will highlight our experience in this setting, including how our CAP BAP accredited research laboratory activities co-exist with our LAP accredited/CLIA certified clinical laboratory activities.

Case Study by Dr. Jewell: The Cancer Moonshot Biospecimen Core Resource
A biospecimen core resource performs an array of tasks to meet the biospecimen management needs of a research project. When research projects are based on human biospecimens from research participants, clinically relevant findings may arise either as part of the intended project or incidentally. Like many biobanks that are involved in clinical trials, the advancement of research technologies continues to push the need for biobanks to teeter between the research and clinical utility of patient samples. The Van Andel Research Institute serves as the biospecimen core resource (BCR) for the Cancer Moonshot Biobank, which conducts clinical biomarker assays for enrolled research participants. This presentation will discuss the organization, description of services and the design of the BCR to develop and maintain the capability for clinical testing results to be returned to patients.