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Last Updated: 11/04/14

Timeline and New Mission

the caHUB timeline chart.

Facing significant budgetary constraints and seeking to reform the priorities of the Institute, the NCI Director performed a thorough review of all programs under his purview and charged caHUB with a new mission in early 2011. As initially envisioned, caHUB would collect, using state-of-the-science SOPs, high-quality human biospecimens and associated data that would be accessible by the research and product-development communities through a transparent, scientifically competitive process. An integral part of this vision was the continued improvement of the state-of-the-science of evidence-based biobanking and quality standards for fit-for-purpose human biospecimens through caHUB research and development.

The new vision of caHUB focuses primarily on the portion of its mission pertaining to research and development. caHUB will address systematically the gaps in knowledge needed to improve the state-of-the-science and to strengthen the standards for human biobanking. It will use a systematic and coordinated approach to investigating the impact of procedural and environmental factors on biospecimen analysis results. The approach will be based on a logical conceptual framework that is specimen-type, biomolecule-type, and analysis-platform-type specific. This framework can be used simultaneously to coordinate and synergize complementary efforts by other groups worldwide with whom the OBBR has built relationships. From this knowledge framework, evidence-based protocols will be developed for the entire research community. These tools will empower investigators to collect human biospecimens for their own use that are fit for their specific scientific purposes.

Original Concept: caHUB as a National Biospecimen Resource

Original Concept: caHUB as a National Biospecimen Resource

New Concept: caHUB as a Center for Biospecimen Science and Standards

New Concept: caHUB as a Center for Biospecimen Science and Standards