Monday, March 28, 2011 |
7:30 a.m. - 8:30 a.m. |
Registration and Continental Breakfast |
8:30 a.m. - 9 a.m. |
Welcome and BRN Program Update
Helen M. Moore, Ph.D.
National Cancer Institute, NCI |
9:00 a.m. - 10:00 a.m. |
Biospecimens: A Crucial Resource for Advances in Molecular Diagnostics, Imaging, and Therapeutics
George Poste, D.V.M., Ph.D., D.Sc.
Arizona State University
Question-and-Answer Session |
10:00 a.m. - 10:20 a.m. |
Break
Session: BRN-Supported Studies in Cancer Tissue Molecular Integrity
Session Chair: Jim Vaught, Ph.D.
National Cancer Institute, NIH |
10:20 a.m. - 10:50 a.m. |
Effects of Intra-Operative Ischemia on Key Proteins
Hartmut Juhl, M.D., Ph.D.
Indivumed
Question-and-Answer Session |
10:50 a.m. - 11:20 a.m. |
Intrinsic and Extrinsic Controls for FFPE Tissue
David L. Rimm, M.D., Ph.D.
Yale University
Question-and-Answer Session |
11:20 a.m. - 11:50 a.m. |
Effects of Biospecimen Integrity, Intratumoral Heterogeneity, and Analytical Variance on Micoarray-Based Pharmacogenomics Tests of Breast Cancer
William Fraser Symmans, M.D.
The University of Texas M.D. Anderson Cancer Center
Christos Hatzis, Ph.D.
Nuvera Biosciences
Question-and-Answer Session |
11:50 a.m. - 12:20 p.m. |
Rapid Methods for the Assessment of Tissue Quality
Charles F. Saller, Ph.D.
Analytical Biological Services, Inc.
Question-and-Answer Session |
12:20 p.m. - 1:45 p.m. |
Meet-the-Experts Lunch
Session: International Biospecimen Research and Late-Breaking Abstracts
Session Chair: Marianne K. Henderson, M.S.
National Cancer Institute, NIH |
1:45 p.m. - 2:00 p.m. |
ISBER Initiatives in Biorepository Communication, Education, and Training
Marianne K. Henderson, M.S.
National Cancer Institute, NIH |
2:00 p.m. - 2:30 p.m. |
EU Project SPIDIA Update - Standardization and Improvement of Generic Preanalytical Tools and Procedures for In Vitro Diagnostics
Uwe Oelmuller, Ph.D.
QIAGEN
Question-and-Answer Session |
2:30 p.m. - 2:45 p.m. |
Tissue Procurement Quality Assurance in the Midwestern Division Cooperative Human Tissue Network (CHTN)
Kelly Senecal
The Ohio State University
Question-and-Answer Session |
2:45 p.m. - 3:00 p.m. |
A Survey of Tissue Specimen Collection Techniques: Impact on Biomarker Data Quality
Antonette Allen, M.S.
Catholic Health Initiatives Institute for Research and Innovation
Question-and-Answer Session |
3:00 p.m. - 3:15 p.m. |
Implementing Standard Preanalytical Coding Into the CanSto Database
Ruth Pe Benito, M.P.A.
Garvan Institute of Medical Research
Question-and-Answer Session |
3:15 p.m. - 3:30 p.m. |
Bringing Biobanks to Life
Richard Schlegel, M.D., Ph.D.
Georgetown University
Question-and-Answer Session |
3:30 p.m. -3:50 p.m. |
Coffee Break
Session: Late-Breaking Abstracts in Biospecimen Science
Session Chair: Fay Betsou, Sc.D.
Integrated BioBank of Luxembourg |
3:50 p.m. - 4:05 p.m. |
Investigating the Impact of Preanalytical Variables on Protein Quality of Human Tissue Samples
Sibylle Guendisch, Ph.D.
Technical University of Munich
Question-and-Answer Session |
4:05 p.m. - 4:20 p.m. |
Snap-Embalming Tissue - Cell Signaling and Tissue Morphology Frozen in Time at Room Temperature
Claudius Mueller, Ph.D.
George Mason University
Question-and-Answer Session |
4:20 p.m. - 4:35 p.m. |
An Evaluation of the PAXgene Fixation System: Can We Preserve Morphology and Nucleic Acid Integrity?
William Mathieson, Ph.D., M.S.
Imperial College London
Question-and-Answer Session |
4:35 p.m. - 4:50 p.m. |
Glycoproteomic Analysis of Formalin-Fixed and Paraffin-Embedded Tissues and OCT-Embedded Frozen Tissues
Yuan Tian, Ph.D.
Johns Hopkins School of Medicine
Question-and-Answer Session |
4:50 p.m. - 5:05 p.m. |
Protocols for Analysis of Whole Saliva Gene Expression
Andrew W. Bergen, Ph.D.
SRI International
Question-and-Answer Session |
5:05 p.m. - 5:20 p.m. |
The Effects of Delayed Processing of Whole Blood Samples on Immune Function and Multiplex Cytokine Assays
Kerri J. Penrose
National Cancer Institute at Frederick
Question-and-Answer Session |
5:20 p.m. - 5:35 p.m. |
Day 1 Closing Remarks
Helen M. Moore, Ph.D.
National Cancer Institute, NIH |
5:35 p.m. - 7:00 p.m. |
Poster Session and Light Reception |
Tuesday, March 29 |
7:30 a.m. - 8:00 a.m. |
Registration and Continental Breakfast |
8:00 a.m. - 9:00 a.m. |
Continental Breakfast Discussion Tables: Informal Discussions of Attendee-Driven Topics
Session: BRN-Supported Studies in Blood, Plasma, and Serum Molecular Integrity
Session Chair: Mark Cosentino, Ph.D., D.P.M.
National Cancer Institute at Frederick |
9:00 a.m. - 9:30 a.m. |
Investigations Into the Effects of Blood Specimen Handling Procedures on Protein Integrity
Daniel Chelsky, Ph.D.
Caprion Proteomics, Inc.
Question-and-Answer Session |
9:30 a.m. - 10:00 a.m. |
Credentialing Plasma and Serum Biospecimen Banks for Proteomics Analyses
Katherine Williams, Ph.D.
University of California, San Francisco
Susan J. Fisher, Ph.D.
University of California, San Francisco
Question-and-Answer Session |
10:00 a.m. - 10:30 a.m. |
Effects of Preanalytic Variables on Circulating MicroRNAs
Hua Zhao, Ph.D.
Roswell Park Cancer Institute
Question-and-Answer Session |
10:30 a.m. - 10:50 a.m. |
Break
Session: BRN-Supported Research Studies in Cancer Tissue Preanalytical Variables
Session Chair: Helen M. Moore, Ph.D.
National Cancer Institute, NCI |
10:50 a.m. - 11:20 a.m. |
Project Overview and Experimental Design
Jennifer L. Hunt, M.D., M.Ed.
Massachusetts General Hospital
Question-and-Answer Session |
11:20 a.m. - 11:50 a.m. |
Annotating the Biospecimen Lifecycle: A Case Study
Howard Greenman, M.B.A.
Provia Laboratories
Question-and-Answer Session |
11:50 a.m. - 1:30 p.m. |
Lunch and Poster Session
Session: Overcoming Challenges to High-Quality Biospecimen Collection
Session Chair: David G. Hicks, M.D.
University of Rochester Medical Center |
1:30 p.m. - 2:00 p.m. |
Empowering Community Pathologists To Successfully Conduct Molecularly Informed Personalized Medicine
Thomas P. Malone, M.B.A.
College of American Pathologists
Question-and-Answer Session |
2:00 p.m. - 2:30 p.m. |
The Importance of Biospecimen Quality in FDA Submissions
Abraham Tzou, M.D.
U.S. Food and Drug Administration
Question-and-Answer Session |
2:30 p.m. - 3:00 p.m. |
Tackling the Widespread and Critical Impact of Batch Effects in High-Throughput Data
Rafael A. Irizarry, Ph.D.
Johns Hopkins University
Question-and-Answer Session |
3:00 p.m. - 3:30 p.m. |
Break |
3:30 p.m. - 4:30 p.m. |
The Revisioning of caHUB as a Center for Biospecimen Science and Standards Development
Carolyn C. Compton, M.D., Ph.D.
National Cancer Institute, NIH
Question-and-Answer Session |
4:30 p.m. |
Closing Remarks
Helen M. Moore, Ph.D.
National Cancer Institute, NIH |
