7:30 a.m.

Registration and Continental Breakfast

Introductory Session
Chair: Carolyn C. Compton, M.D., Ph.D.
Director
Office of Biorepositories and Biospecimen Research
National Cancer Institute, NIH

8:30 a.m. - 9:00 a.m.

Welcome Address
Anna D. Barker, Ph.D.
Deputy Director
National Cancer Institute, NIH

9:00 a.m. - 9:30 a.m.

Symposium Overview and BRN Program Update
PDF Document: 3.17 MB
Helen M. Moore, Ph.D.
Director
Biospecimen Research Network
National Cancer Institute, NIH

9:30 a.m. - 10:00 a.m.

Why Do We Need Research in Preservation Science?
PDF Document: 1.08 MB
Allison Hubel, Ph.D.
Department of Mechanical Engineering
University of Minnesota

Question-and-Answer Session

10:00 a.m. - 10:30 a.m.

Assessing Biospecimen Quality
PDF Document: 2.53 MB
Andrew I. Brooks, Ph.D.
Director
Bionomics Research and Technology Center
Robert Wood Johnson Medical School

Question-and-Answer Session

10:30 a.m. - 10:45 a.m.

Coffee Break

Blood Biospecimen Science: I
Chair: Helen M. Moore, Ph.D.
Director
Biospecimen Research Network
National Cancer Institute, NIH

10:45 a.m. - 11:15 a.m.

Credentialing Plasma and Serum Biospecimen Banks for Proteomics Analysis
PDF Document: 265 KB
Katherine Williams, Ph.D.
Sandler-Moore Mass Spectrometry Core Facility
University of California, San Francisco

Question-and-Answer Session

11:15 a.m. - 11:45 a.m.

Investigations Into the Effects of Blood Specimen Handling Procedures on Protein Integrity
PDF Document: 345 KB
Christopher Becker, Ph.D.
PPD, Inc.

Question-and-Answer Session

11:45 a.m. - 12:15 p.m.

Hot Topic in Biospecimen Science (selected from submitted abstracts)

Standard Operating Preanalytical Procedures for Protein Profiling and DNA Studies: The Experience of the Interinstitutional Multidisciplinary BioBank (BioBIM)
PDF Document: 2.66 MB
Fiorella Guadagni, M.D., Ph.D., M.B.A.
BioBIM, Department of Laboratory Medicine and Advanced Biotechnologies
Istituto di Ricovero e Cura a Carattere Scientifico

Question-and-Answer Session

12:15 p.m. - 1:30 p.m.

Meet-the-Experts Lunch

1:30 p.m. - 2:00 p.m.

Biospecimen Reporting for Improved Study Quality (BRISQ): BRN Committee Report
PDF Document: 187 KB
Scott D. Jewell, Ph.D.
Associate Director for Biorepository and Biospecimen Resources
Research Associate Professor
College of Medicine
The Ohio State University

Question-and-Answer Session

Tissue Biospecimen Science: I
Chair: Scott D. Jewell, Ph.D.
Associate Director for Biorepository and Biospecimen Resources
Research Associate Professor
College of Medicine
The Ohio State University

2:00 p.m. - 2:30 p.m.

Tissue Intraoperative Factors
PDF Document: 2.90 MB
Hartmut Juhl, M.D., Ph.D.
Chief Executive Officer
Indivumed GmbH

Question-and-Answer Session

2:30 p.m. - 3:00 p.m.

How to Improve Intraoperability of Biobanks: The Role of Standardization of Preanalytical Variables
PDF Document: 2.43 MB
Kurt Zatloukal, M.D.
Professor of Pathology
Institute of Pathology
Medical University of Graz, Austria

Question-and-Answer Session

3:00 p.m. - 3:15 p.m.

Coffee Break

Information Solutions for Biospecimen Science
Chair: Ian Fore, D.Phil.
Center for Biomedical Informatics and Information Technology
National Cancer Institute, NIH

3:15 p.m. - 3:45 p.m.

An Informatics Framework for Biospecimen Science
PDF Document: 1.63 MB
Paul Fearn, M.B.A.
National Library of Medicine Informatics Research Fellow
University of Washington

Question-and-Answer Session

3:45 p.m. - 4:15 p.m.

Development and Real-World Use of a System for Tracking Biospecimens and Biospecimen Data
PDF Document: 1.84 MB
Mark A. Watson, M.D., Ph.D.
Associate Professor of Pathology and Immunology
Genome Sequencing Center
Washington University School of Medicine

Question-and-Answer Session

4:15 p.m. - 4:45 p.m.

Hot Topic in Biospecimen Science (selected from submitted abstracts)

Informatics-Guided Workflow for Procuring Biospecimens From Cancer Patients
PDF Document: 522 KB
K. Stephen Suh, Ph.D.
Cancer Center
Hackensack University Medical Center

Question-and-Answer Session

4:45 p.m. - 5:15 p.m.

Hot Topic in Biospecimen Science (selected from submitted abstracts)

Integrating Biospecimen Collection, Clinical Information, and Proteomics for Cancer Biomarker Research
PDF Document: 1.04 MB
John Springer, Ph.D.
Assistant Professor
Department of Computer and Information Technology
Purdue University

Question-and-Answer Session

5:15 p.m.

Light Reception and Poster Session

7:30 a.m.

Continental Breakfast

Biospecimen Science Around the World
Chair: Jim Vaught, Ph.D.
Deputy Director
Office of Biorepositories and Biospecimen Research
National Cancer Institute, NIH

8:30 a.m. - 9:00 a.m.

Introduction to Topic: The State of Biospecimen Science
PDF Document: 1.42 MB
Brian J. Clark, MBChB, FRCPath
Chief Executive Officer
onCore UK

Question-and-Answer Session

9:00 a.m. - 9:30 a.m.

ISBER Biospecimen Working Group Report
PDF Document: 987 KB
Fay Betsou, Ph.D., HDR
Laboratory Manager
Biobanque de Picardie

Question-and-Answer Session

9:30 a.m. - 10:00 a.m.

Standardization and Improvement of Generic Preanalytical Tools and Procedures for In Vitro Diagnostics-EU Project SPIDIA
PDF Document: 270 KB
Uwe Oelmueller, Ph.D.
Senior Director
Research and Development
Diagnostic Sample Preparation and Stabilization
QIAGEN

Question-and-Answer Session

10:00 a.m. - 10:30 a.m.

Banking AIDS-Related Malignancies in Sub-Saharan Africa
PDF Document: 1.69 MB
Leona W. Ayers, M.D.
Professor
College of Medicine
The Ohio State University

Question-and-Answer Session

10:30 a.m. - 10:45 a.m.

Coffee Break

Tissue Biospecimen Science: II
Chair: Sherilyn J. Sawyer, Ph.D.
Office of Biorepositories and Biospecimen Research
National Cancer Institute, NIH

10:45 a.m. - 11:15 a.m.

Intrinsic Controls for Formalin Fixed, Paraffin Embedded Tissue
PDF Document: 3.72 MB
David L. Rimm, M.D.-Ph.D.
Yale University School of Medicine

Question-and-Answer Session

11:15 a.m. - 11:45 a.m.

Effects of Ex Vivo Duration and Host Organ Contamination on RNA Expression Profiles of Breast Cancer
PDF Document: 954 KB
W. Fraser Symmans, M.D.
The University of Texas M.D. Anderson Cancer Center

Question-and-Answer Session

11:45 a.m. - 12:15 p.m.

Hot Topic in Biospecimen Science (selected from submitted abstracts)

The Multiple Myeloma Research Consortium (MMRC) Tissue Bank: Five Years' Experience
Daniel Auclair, Ph.D.
Multiple Myeloma Research Consortium

Question-and-Answer Session

12:15 p.m. - 1:15 p.m.

Lunch

Blood Biospecimen Science: II
Chair: Katherine Williams, Ph.D.
Sandler-Moore Mass Spectrometry Core Facility
University of California, San Francisco

1:15 p.m. - 1:45 p.m.

Blood Preanalytical Studies/Trials
PDF Document: 2.59 MB
Mario Pazzagli, Ph.D.
Professor of Clinical Biochemistry and Clinical Molecular Biology
University of Florence

Question-and-Answer Session

1:45 p.m. - 2:15 p.m.

Plasma Stability Studies
PDF Document: 578 KB
Lisa J. Zimmerman, Ph.D.
Research Assistant Professor of Biochemistry
Vanderbilt University

Question-and-Answer Session

2:15 p.m. - 2:45 p.m.

New Methods for Sampling Frozen Blood Tubes
PDF Document: 1.36 MB
Dale N. Larson, M.S.
Director of Biomedical Systems
The Charles Stark Draper Laboratory, Inc.

Question-and-Answer Session

2:45 p.m. - 3:15 p.m.

Hot Topic in Biospecimen Science (selected from submitted abstracts)

The Effect of Processing Delays on Global Gene Expression Patterns in PBMCs
PDF Document: 610 KB
Michael G. Barnes, Ph.D.
Director
Cincinnati Biorepository
Cincinnati Children's Hospital Medical Center

Question-and-Answer Session

3:15 p.m. - 3:30 p.m.

Coffee Break

The Cancer Human Biobank (caHUB)

3:30 p.m. - 3:50 p.m.

Overview of caHUB
PDF Document: 1.49 MB
Carolyn C. Compton, M.D., Ph.D.
Director
Office of Biorepositories and Biospecimen Research
National Cancer Institute, NIH

3:50 p.m. - 4:10 p.m.

caHUB Working Group Update
PDF Document: 254 KB
Elaine W. Gunter, MT(ASCP)
Founder and President
Specimen Solutions, LLC

4:10 p.m. - 4:30 p.m.

Developing caHUB Biospecimen SOPs
PDF Document: 392 KB
James A. Robb, M.D.
Consulting Pathologist
Office of Biorepositories and Biospecimen Research
National Cancer Institute, NIH

4:30 p.m. - 4:50 p.m.

Biospecimen Science and the caHUB: A Patient Advocate's View
PDF Document: 462 KB
Deborah Collyar
President, PAIR: Patient Advocates in Research
Specialized Program of Research Excellence
Patient Advocate Research Team Program

4:50 p.m. - 5:20 p.m.

Panel Discussion
Carolyn C. Compton, M.D., Ph.D.
Director
Office of Biorepositories and Biospecimen Research
National Cancer Institute, NIH

Elaine W. Gunter, MT(ASCP)
Founder and President
Specimen Solutions, LLC

James A. Robb, M.D.
Consulting Pathologist
Office of Biorepositories and Biospecimen Research
National Cancer Institute, NIH

Deborah Collyar
Program Director
Specialized Program of Research Excellence
Patient Advocate Research Team Program

5:20 p.m.

Closing Remarks and Next Steps
Helen M. Moore, Ph.D.
Director
Biospecimen Research Network
National Cancer Institute, NIH